- Delegated Regulation (EU) 2023/707 added six hazard classes, with new statements EUH380 to EUH451.
- Deadline for substances already on the market: 1 November 2026. Mixtures already on the market: 1 May 2028.
- New products have had to comply since 1 May 2025 (substances) and 1 May 2026 (mixtures).
- The SDS format itself is unchanged: REACH Annex II as amended by Regulation (EU) 2020/878 still applies.
Delegated Regulation (EU) 2023/707 added new hazard classes to the CLP Regulation for the first time since it was adopted. They cover properties the EU previously handled only through REACH: endocrine disruption, persistence and bioaccumulation, and persistence and mobility in water.
EUH380 Category 1 · EUH381 Category 2DangerWarningMixtures classified from 0.1% (category 1), 1% (category 2)EUH430 Category 1 · EUH431 Category 2DangerWarningMixtures classified from 0.1% (category 1), 1% (category 2)EUH440DangerMixtures classified from 0.1%EUH441DangerMixtures classified from 0.1%EUH450DangerMixtures classified from 0.1%EUH451DangerMixtures classified from 0.1%These classes have no pictogram. They are communicated with a signal word ("Danger" for most, "Warning" for the category 2 endocrine classes), an EUH hazard statement and precautionary statements.
The deadlines
| Placed on the market from | Already on the market | |
|---|---|---|
| Substances | 1 May 2025 | 1 November 2026 |
| Mixtures | 1 May 2026 | 1 May 2028 |
"Already on the market" means products placed on the EU market before the first date. For substances, that grace period ends on 1 November 2026.
When does a mixture get classified?
For mixtures, the classes work much like other health hazards: a mixture is classified when it contains a classified ingredient at or above the generic concentration limit. That is 0.1% for endocrine disruptor category 1, PBT, vPvB, PMT and vPvM ingredients, and 1% for endocrine disruptor category 2 ingredients, unless a specific concentration limit applies.
What changes on the SDS
- Sections 2.1 and 2.2: the new classification, signal word, EUH statement and precautionary statements.
- Section 3: the classification of each listed ingredient, including the new classes.
- Sections 11 and 12: the information on endocrine-disrupting, PBT and PMT properties.
- Section 16: the revision note and the full text of the new statements.
Related changes to watch
The CLP revision, Regulation (EU) 2024/2865, has applied since 1 July 2026. Among other things, substances made of more than one constituent must now be classified for these classes from their known constituents, and suppliers must set acute toxicity estimates and M-factors. Its new label-format rules, such as minimum font sizes, were postponed to 1 January 2028 by Regulation (EU) 2025/2439.
The SDS format itself has not changed: REACH Annex II as amended by Regulation (EU) 2020/878 is still the current version. The deadline is set by EU law and also applies in Northern Ireland; it does not apply automatically in Great Britain.
Checklist before 1 November 2026
- Ask your raw-material suppliers whether any substance you buy is classified in the new classes.
- For substances you place on the EU market, assess and update classification, labels and SDSs.
- For mixtures, plan updates now. The 2028 date applies only to mixtures already on the market before 1 May 2026.
Sources
General information, not legal advice. Checked against the official sources above on 7 October 2026. Rules change: for your own products, ask for a spot-check.
